Lesson 1: Aromatic Reactions

Aromatic Reactions

In this chapter we will learn new reactions applicable to organic compounds.

The general mechanism of EAS reactions

REACTIONS 1-3: Halogenation, Nitration, and Sulfonation

figure1-edited

The mechanism of chlorination

The mechanism of nitration

REACTION 4: Friedel-Crafts Alkylation

FCalk

FC alkylation mechanism

FC alkylation (under acid conditions) mechanism

FC alkylation (with rearrangement) mechanism

REACTION 5: Friedel-Crafts Acylation

FCacylation-edited

FC acylation mechanism

REACTION 6: Reduction of ketones (Clemmensen Reduction)

clemmensen red

What happens when you run an EAS reaction on an aromatic compound other than benzene? Where does the new group add?

directors1

A few definitions we need first

Ortho, meta, and para describe positions around the benzene ring (as compared to a starting point - R)

directors2

 

 

 

directors3

Why?

directors5directors6-edited

YOU TRY:

(if o/p is available assume the para product will be the major isomer):

 



problem1

REACTIONS 7-10: Side chain reactions and benzene reduction

sidechain reactions

Leave a Reply

Your email address will not be published. Required fields are marked *

css.php